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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24A All Species: 11.52
Human Site: S99 Identified Species: 19.49
UniProt: O95486 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95486 NP_068817.1 1093 119749 S99 A S N P V T P S L H S G P A P
Chimpanzee Pan troglodytes XP_527165 1093 119711 L99 A S N P V T P L L H S G P A P
Rhesus Macaque Macaca mulatta XP_001109620 1093 119674 L99 A S N P V T P L L H S G P A P
Dog Lupus familis XP_850736 1100 120445 P99 G Q T L Y R P P V A S N P V T
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 S99 T S G P V L P S L H S G P V P
Rat Rattus norvegicus NP_001099250 1089 118849 S99 T S S P V P P S L H S G P V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510651 1234 134485 V204 D S N L M A P V P Q M P S L P
Chicken Gallus gallus XP_414630 1100 120006 T102 S G S P V Q Q T G P V P Q V L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 Y102 P P H A N S H Y Q H T Q Q P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 M165 P P T G A P P M G Q N Y M P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 S99 P S S N S F P S P A Y G P P G
Baker's Yeast Sacchar. cerevisiae P40482 926 103617
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 P14 N D G Y G Q Y P P Q Q Y G E Q
Conservation
Percent
Protein Identity: 100 99.4 97.7 92.1 N.A. 88.3 88.2 N.A. 69.1 74 N.A. 59.5 N.A. N.A. 44.7 N.A. 28.7
Protein Similarity: 100 99.8 98.2 94.2 N.A. 92.4 92 N.A. 76.2 83 N.A. 71.4 N.A. N.A. 59.4 N.A. 43
P-Site Identity: 100 93.3 93.3 20 N.A. 73.3 73.3 N.A. 26.6 13.3 N.A. 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 93.3 93.3 26.6 N.A. 73.3 80 N.A. 33.3 33.3 N.A. 26.6 N.A. N.A. 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 34.5 29.7 31.7
Protein Similarity: N.A. N.A. N.A. 53.5 48.2 49.7
P-Site Identity: N.A. N.A. N.A. 33.3 0 0
P-Site Similarity: N.A. N.A. N.A. 40 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 8 8 8 0 0 0 15 0 0 0 22 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 15 8 8 0 0 0 15 0 0 43 8 0 15 % G
% His: 0 0 8 0 0 0 8 0 0 43 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 15 0 8 0 15 36 0 0 0 0 8 8 % L
% Met: 0 0 0 0 8 0 0 8 0 0 8 0 8 0 0 % M
% Asn: 8 0 29 8 8 0 0 0 0 0 8 8 0 0 0 % N
% Pro: 22 15 0 43 0 15 65 15 22 8 0 15 50 22 43 % P
% Gln: 0 8 0 0 0 15 8 0 8 22 8 8 15 0 8 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 50 22 0 8 8 0 29 0 0 43 0 8 0 8 % S
% Thr: 15 0 15 0 0 22 0 8 0 0 8 0 0 0 8 % T
% Val: 0 0 0 0 43 0 0 8 8 0 8 0 0 29 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 8 8 0 0 8 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _